A knowledgebase of RNA editing events that have been proven to affect hematopoietic differentiation

This module contains 8 experimentally validated RNA editing events, which include 7 mRNAs and 1 lncRNA, and are activities involved with 3 RNA editing enzymes. The informations are curated from multiple publications.



Category

Editing Type:
Gene biotype:
Enzyme:
Editing
pattern		 Species Gene
name		 Gene
type		 Genomic
region		 AA
change		 Enzyme Editing
site(s)		 Editing
type		 Editing
effect		 PMID Chr
MPP-specific mouse Azin1 mRNA Serine-Glycine ADAR1 2 A-to-I They sorted 12 murine adult hematopoietic cell populations at different stages and identified 30796 editing sites through RNA sequencing. The dynamic landscape of the RNA editome comprises stage- and group-specific and stable editing patterns, but undergo 34388251 chr15-38491612
MPP-specific mouse Cog3 mRNA Isokeucine-Valine ADAR1 1 A-to-I They sorted 12 murine adult hematopoietic cell populations at different stages and identified 30796 editing sites through RNA sequencing. The dynamic landscape of the RNA editome comprises stage- and group-specific and stable editing patterns, but undergo 34388251 chr14-75719719
MPP-specific mouse Igbp1 mRNA Lysine-Glutamicacid ADAR1 1 A-to-I They sorted 12 murine adult hematopoietic cell populations at different stages and identified 30796 editing sites through RNA sequencing. The dynamic landscape of the RNA editome comprises stage- and group-specific and stable editing patterns, but undergo 34388251 chrx-100494429
MPP-specific mouse Rrp15 mRNA Glutamicacid-Glycine ADAR1 1 A-to-I They sorted 12 murine adult hematopoietic cell populations at different stages and identified 30796 editing sites through RNA sequencing. The dynamic landscape of the RNA editome comprises stage- and group-specific and stable editing patterns, but undergo 34388251 chr1-186749196
MPP-specific mouse H19 ncRNA NA ADAR1 1 A-to-I They sorted 12 murine adult hematopoietic cell populations at different stages and identified 30796 editing sites through RNA sequencing. The dynamic landscape of the RNA editome comprises stage- and group-specific and stable editing patterns, but undergo 34388251 chr7-142577095
bone marrow-derived macrophage mouse cd36 mRNA NA APOBEC1 1 C-to-U editing alters gene expression by modulating translation (but not RNA stability or localization). 29167373 chr5:17288970-17288939
bone marrow-derived macrophage mouse app mRNA NA APOBEC1 >1 C-to-U editing alters gene expression by modulating translation (but not RNA stability or localization). 29167373 chr16:84955027-84955113
umbilical cord blood mononuclear cell human WT1 mRNA NA NA 1 A-to-G They observed two alternative G-to-A changes, namely c.1303G>A and c.1586G>A in cDNA clones and found them to be recurrent in a series of 21 umbilical cord blood mononuclear cell (CBMC) samples studied. Two less conserved U-to-C changes were also obs 25807502 Exons 6 to 10 of WT1-cDNA (c.1528)
umbilical cord blood mononuclear cell human WT1 mRNA C300R NA 1 T-to-C They observed two alternative G-to-A changes, namely c.1303G>A and c.1586G>A in cDNA clones and found them to be recurrent in a series of 21 umbilical cord blood mononuclear cell (CBMC) samples studied. Two less conserved U-to-C changes were also observed 25807502 Exons 6 to 10 of WT1-cDNA (c.1388)
umbilical cord blood mononuclear cell human WT1 mRNA NA NA 1 T-to-C They observed two alternative G-to-A changes, namely c.1303G>A and c.1586G>A in cDNA clones and found them to be recurrent in a series of 21 umbilical cord blood mononuclear cell (CBMC) samples studied. Two less conserved U-to-C changes were also observed 25807502 Exons 6 to 10 of WT1-cDNA (c.1402)
umbilical cord blood mononuclear cell human WT1 mRNA NA APOBEC3A 1 G-to-A They observed two alternative G-to-A changes, namely c.1303G>A and c.1586G>A in cDNA clones and found them to be recurrent in a series of 21 umbilical cord blood mononuclear cell (CBMC) samples studied. Two less conserved U-to-C changes were also observed 25807502 Exons 6 to 10 of WT1-cDNA (c.1303)
umbilical cord blood mononuclear cell human WT1 mRNA D396N NA 1 G-to-A They observed two alternative G-to-A changes, namely c.1303G>A and c.1586G>A in cDNA clones and found them to be recurrent in a series of 21 umbilical cord blood mononuclear cell (CBMC) samples studied. Two less conserved U-to-C changes were also observed 25807502 Exons 6 to 10 of WT1-cDNA (c.1586)